Sunday, April 28, 2013

SARMs + 5-alpha reductase blockers = a more effective cure for ...

Hello, have someone of you tried the combination of SARMS with 5-AR blockers (finasteride, Dutasteride)? I wonder, because I would like to share my experience.

Last year in summer, as I long-time minoxidil user for nearly 16 years, I wanted to regrow hair in my temples with the help of finasteride. I began in late June on 1 mg/day. After few weeks of mild shedding, I suddenly started to experience an almost explosive regrowth in early August. Well, it was mostly thin vellus hair, but I couldn't believe my eyes, because the hair was growing even on the sides of my forehead, which I previously regarded as utterly impossible. I thought that in the following months, I could get my NW 1.5 hairline to a cosmetically acceptable NW 1.

Alas, it didn't happen. In early September the regrowth stopped and in late October, everything turned upside down by 180 degrees and I started to lose hair in my temples. Now, I won't annoy you by the description of the following 6 months that were an ordeal for me. I still don't know, why I suddenly started to lose hair. But I think that I already know, why I was regrowing it in summer: It was not the effect of finasteride, but a concurrent use of finasteride with SARMS (Ostarine, S4) that I was taking in July and August.

Actually, I thought that the use of SARMS at the beginning of a finasteride therapy was not a good idea, and that SARMS would compromise the effect of finasteride, because in studies done in rats, their effect on prostate was roughly half that of finasteride. But I have no other explanation, because in December I did blood tests and my dihydrotestosterone was 32 ng/dl - an utter joke! In January, I achieved only a marginally lower value - 25 ng/dl, but at a much lower testosterone level. Considering that these values are not much different from the range in adult men (30-85 ng/dl) and considerably higher than those in the average finasteride user (ca. 15 ng/dl), I think that finasteride alone couldn't be responsible for the regrowth. It must have been the combined effect of finasteride and SARMS. The sudden end of this short regrowth phase coincided exactly with the quitting of SARMS, after all. Further, in July, I measured my testosterone and it was markedly suppressed - 50 ng/dl. So, SARMS suppressed testosterone, blocked dihydrotestosterone receptors, and finasteride probably erased the remaining dihydrotestosterone in my blood to such a degree that it was able to wake up my hair follicles. (I have never observed any hair regrowth on SARMS alone before!)

At this moment, the state of my hair is stable. The shedding slowed down and later stopped during March, after I started to add Dutasteride to my daily finasteride regime. Now I am at 0.33 mg/dut day + 1.25 mg fin/day, and my dihydrotestosterone levels finally began to drop (17 ng/dl). I am really curious, if increasing the Dutasteride dosage leads to the same regrowth like during the last summer. At least, I know that it is possible in me. Unfortunately, I don't plan to touch SARMS anymore, because the depressive winter shedding scared me so much that now I am afraid to use whatever anabolic drugs. (It's irrational, I know.) In any case, I think that my story can be an inspiration for other experimenters.


Last edited by EliteFitnessGuy; Today at 11:21 AM.

Source: http://www.elitefitness.com/forum/anabolic-steroids/sarms-5-alpha-reductase-blockers-more-effective-cure-hairloss-1198303.html

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